Year of publication:
2006
Journal name:
Georgia Tech Theses and Dissertations
Mechanotransduction in Engineered Cartilaginous Tissues: In Vitro Oscillatory Tensile Loading
http://smartech.gatech.edu –
Disease and degeneration of articular cartilage and fibrocartilage tissues severely compromise the quality of life for millions of people. Although current surgical repair techniques can address symptoms in the short term, they do not adequately treat degenerative joint diseases such as osteoarthritis. Thus, novel tissue engineering strategies may be necessary to combat disease progression and repair or replace damaged tissue. Read more »
Effect of Strain Magnitude on the Tissue Properties of Engineered Cardiovascular Constructs
http://www.ncbi.nlm.nih.gov –
Mechanical loading is a powerful regulator of tissue properties in engineered cardiovascular tissues. To ultimately regulate the biochemical processes, it is essential to quantify the effect of mechanical loading on the properties of engineered cardiovascular constructs. In this study the Flexercell FX-4000T (Flexcell Int. Corp., USA) straining system was modified to simultaneously apply various strain magnitudes to individual samples during one experiment. Read more »
Year of publication:
2007
Journal name:
Annals of Biomedical Engineering
Category: Cardiovascular Tags: