http://www.nature.com –
Journal name:
Nature Clinical Practice Cardiovascular Medicine
Nuclear transport of transcription factors is a critical step in stem cell commitment to a tissue-specific lineage. While it is recognized that nuclear pores are gatekeepers of nucleocytoplasmic exchange, it is unknown how the nuclear transport machinery becomes competent to support genetic reprogramming and cell differentiation. Here, we report the dynamics of nuclear transport factor expression and nuclear pore microanatomy during cardiac differentiation of embryonic stem cells.
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Created by wpNg
2 years 17 weeks ago
Category:
Stem Cells Tags: