Year of publication:
2005
Journal name:
Molecular Biology Cell
Intracellular Mechanics of Migrating Fibroblasts
http://www.molbiolcell.org –
Cell migration is a highly coordinated process that occurs through the translation of biochemical signals into specific biomechanical events. The biochemical and structural properties of the proteins involved in cell motility, as well as their subcellular localization, have been studied extensively. However, how these proteins work in concert to generate the mechanical properties required to produce global motility is not well understood. Read more »
Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets
http://www.sciencedirect.com –
Background: Sheets of cells move together as a unit during wound healing and embryonic tissue movements, such as those occurring during gastrulation and neurulation. We have used epithelial wound closure as a model system for such movements and examined the mechanisms of closure and the importance of the Rho family of Ras-related small GTPases in this process. Read more »
Year of publication:
2000
Journal name:
Current Biology