http://www.discoveryandinnovation.com – It is generally accepted that transport through the nuclear pore complex (NPC) involves an abundance of phenylalanine–glycine rich protein domains (FG-domains) that serve as docking sites for soluble nuclear transport receptors (NTRs) and their cargo complexes. But the precise mechanism of translocation through the NPC allowing for high speed and selectivity is still vividly debated. Read more »