Year of publication:
2006
Journal name:
Journal of Internal Medicine
Endothelial mechanotransduction, nitric oxide and vascular inflammation
http://www3.interscience.wiley.com –
Numerous aspects of vascular homeostasis are
modulated by nitric oxide and reactive oxygen species
(ROS). The production of these is dramatically
influenced by mechanical forces imposed on the
endothelium and vascular smooth muscle. In this
review, we will discuss the effects of mechanical
forces on the expression of the endothelial cell nitric
oxide synthase, production of ROS and modulation
of endothelial cell glutathione. We will also review
data that exercise training in vivo has a similar effect
as laminar shear on endothelial function and discuss Read more »
Nitric oxide and cyclic nucleotides: Their roles in junction dynamics and spermatogenesis
http://www.ncbi.nlm.nih.gov –
Spermatogenesis is a highly complicated process in which functional spermatozoa (haploid, 1n) are generated from primitive mitotic spermatogonia (diploid, 2n). This process involves the differentiation and transformation of several types of germ cells as spermatocytes and spermatids undergo meiosis and differentiation. Due to its sophistication and complexity, testis possesses intrinsic mechanisms to modulate and regulate different stages of germ cell development under the intimate and indirect cooperation with Sertoli and Leydig cells, respectively. Read more »
Year of publication:
2008
Journal name:
Landes Bioscience