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Analysis of cellular mechanotransduc- tion, the mechanism by which cells convert mechanical signals into biochemical responses, has focused on identification of critical mechanosensitive molecules and cellular components. Stretch-activated ion chan- nels, caveolae, integrins, cadherins, growth factor re- ceptors, myosin motors, cytoskeletal filaments, nuclei, extracellular matrix, and numerous other structures and signaling molecules have all been shown to contrib- ute to the mechanotransduction response.
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