Year of publication:
2009
Journal name:
PubMed
Upstream mechanotaxis behavior of endothelial cells
http://www.ncbi.nlm.nih.gov –
Vascular endothelial cell migration, which plays an important role in vascular remodeling, is known to be regulated by hemodynamic forces in the blood vessels. When shear stress is applied on mouse microvessel endothelial cells (bEnd.3) in vitro, cells exhibit upstream migration behavior with respect to the direction of the flow. To determine how shear stress magnitude influences mechanotaxis of the cells, endothelial cells were exposed to different magnitudes of unidirectional shear stress. Read more »
Category: Endothelial and Smooth Muscle Tags:
Mechanotransduction in endothelial cell migration
http://www3.interscience.wiley.com –
The migration of endothelial cells (ECs) plays an important role in vascular remodeling and regeneration. EC migration can be regulated by different mechanisms such as chemotaxis, haptotaxis, and mechanotaxis. This review will focus on fluid shear stress-induced mechanotransduction during EC migration. EC migration and mechanotransduction can be modulated by cytoskeleton, cell surface receptors such as integrins and proteoglycans, the chemical and physical properties of extracellular matrix (ECM) and cell-cell adhesions. Read more »
Year of publication:
2005
Journal name:
Mechanotransduction in endothelial cell migration
Category: Cell Mechanotransduction Tags: