Year of publication:
1999
Journal name:
The FASEB Journal
Mechanotransduction in Bone - role of the lacuno-canalicular network
http://www.fasebj.org –
The capacity of bone tissue to alter its mass and structure in response to mechanical demands has long been recognized but the cellular mechanisms involved remained poorly understood. Over the last several years significant progress has been made in this field, which we will try to summarize. These studies emphasize the role of osteocytes as the professional mechanosensory cells of bone, and the lacuno-canalicular porosity as the structure that mediates mechanosensing. Read more »
Category: Tissue Mechanotransduction Tags:
Mechanotransduction in endothelial cell migration
http://www3.interscience.wiley.com –
The migration of endothelial cells (ECs) plays an important role in vascular remodeling and regeneration. EC migration can be regulated by different mechanisms such as chemotaxis, haptotaxis, and mechanotaxis. This review will focus on fluid shear stress-induced mechanotransduction during EC migration. EC migration and mechanotransduction can be modulated by cytoskeleton, cell surface receptors such as integrins and proteoglycans, the chemical and physical properties of extracellular matrix (ECM) and cell-cell adhesions. Read more »
Year of publication:
2005
Journal name:
Mechanotransduction in endothelial cell migration
Category: Cell Mechanotransduction Tags: